Microscale thermophoresis device

Oulun yliopisto needs a spectral shift and microscale thermophoresis device for Biocenter Oulu, with a maximum total value of 189,000 EUR (excluding VAT). The device will be used to characterize and quantify nanoparticle interactions, including proteins, in solution without immobilization, and must enable assessment of sample quality and aggregation, differentiating binding events from aggregation. It needs to detect interactions based on changes in the emission spectrum of an excited fluorophore under isothermal conditions and create a microscopic non-isothermal temperature field to determine binding events based on temperature-related intensity changes and fluorescence intensity changes following thermophoresis. The device must have a measurable dynamic range of dissociation constant of at least nM-mM and binding affinity in at least nM-mM range, with low sample consumption (around 10 microlitres) and low nanomole of the labeled target. The contract duration is 36 months. The award criterion is the total price, weighted at 100%.

Näytteenkäsittelyautomaatti (pipetointirobottilaitteisto) LC-MS/MS analyysimenetelmiin

Fimlab Laboratoriot Oy tarvitsee näytteenkäsittelyautomaatin kliinisten näytteiden esikäsittelyyn ennen LC-MS/MS-analyysiä Tampereen laboratorioon. Hankintaan sisältyy laitteiston toimitus, asennus, käyttöönotto, koulutus, tuki- ja huoltopalvelut sekä tarvikkeet ja lisävarusteet. Laitteiston ja tarvikkeiden sopimus tehdään kahdeksi vuodeksi, ja sitä voidaan jatkaa toistaiseksi voimassa olevana tarvikkeiden ja palvelujen osalta. Huolto- ja palvelusopimus tehdään viideksi vuodeksi, ja sitä voidaan jatkaa toistaiseksi voimassa olevana. Hankinnan arvioitu kokonaisarvo on enintään 610 000 euroa. Valintaperusteena on kokonaistaloudellinen edullisuus, eli halvin hinta, joka lasketaan laitekokonaisuuden, tarvikkeiden ja palveluiden yhteenlasketusta hinnasta arvioidulla hankintamäärällä.

Flow imaging microscope

Suomen ympäristökeskus needs a flow imaging microscopy system for morphological analysis and numerical estimation of particles in water (size distribution 2µm – 1 mm) under laboratory and field conditions in Helsinki-Uusimaa, with a maximum total value of 150,000 EUR. The system must be able to image plankton and other particles as color images, calculate indicators related to cell and particle size, pigmentation, color, and shape, and process large sample volumes efficiently. It must also separate phytoplankton cells using chlorophyll fluorescence, enable the use of fluorescent dyes (FITC), allow real-time monitoring of analytics for quality control, and support basic analytics and classification of particle data through its software. The award criterion is price (100%).

Benchtop flow cytometry cell analyzer for immunology, allergy, and cell-based assay research

Danmarks Tekniske Universitet (DTU) needs a benchtop flow cytometry cell analyzer for multicolour immunophenotyping, basophil activation testing, rare-event analysis, plate-based acquisition, and future development of complex immune-cell assays, with a maximum total value of 1,600,000 DKK. The instrument must support robust analysis of human and animal research samples, including low-frequency immune-cell populations and activation-marker readouts, and will be delivered in the Copenhagen area. Becton Dickinson A/S likely has a similar contract today. Award criteria are Price (30%), System (45.5%), Process Monitoring and Control (17.5%), and Delivery (7%). Tenderers must have had a net turnover of at least 3,000,000 DKK and positive equity for each of the last 3 audited financial years.

Multivessel bioreactor system

Tampere University Foundation sr needs a multivessel bioreactor system for bacterial (co-)cultivations, allowing controlled transitions between aerobic and anaerobic phases. The system should include 2 autoclavated glass vessels (working volume 50-200 mL), vessel headplates with necessary ports for mechanical mixer, gas supply, sensors, feed, sampling, and exhaust lines, as well as software to operate the system. Delivery and on-site services, including installation and user's training, are also required. The system will be delivered to Pirkanmaa, Finland. Offers will be evaluated based on comparison price (25%) and technical features and support (75%).